Foster's Home for Imaginary Friends has been mentioned in other TV shows and media.
- Codename: Kids Next Door: In "Operation: T.R.I.C.Y.C.L.E.", Numbuh 4 mocks what he believes is Tommy with his tricycle, saying, "Hey, doofus! You're going the wrong way if you're looking for Foster's Home for Lame Bicycles!"
- MAD: In "Batman Family Feud", one of the shows on the guide is a pun on Foster's named "Frosty Foster's Home for Imaginary Icecream". Also in "Once Upon a Toon", Bloo appears as one of the classic Cartoon Network characters.
- The Grim Adventures of Billy & Mandy: In "Reap Walking", Grim watches a parody of Foster's named "Fister's House for Crazy Weirdo Made-Up People", where in the show had "crazy weirdo made-up people" laughing and charting, then after that the house explodes.
- Robot Chicken: In Joel Hurwitz, a short parody of Foster's Home for Imaginary Friends is featured. The skit involves a girl adopting an imaginary version of Tyler Durden from the film Fight Club. Bloo, Eduardo, Coco, Wilt, and Madame Foster all appear but only Madame Foster talks in the sketch.